DEPARTMENT OF HEALTH AND HUMAN SERVICES
NATIONAL INSTITUTES OF HEALTH
NATIONAL INSTITUTE OF MENTAL HEALTH

Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS)

Neuropsychopharmacological approaches to modulating cognition in schizophrenia: Approaches to identifying promising compounds

National Institute of Health (NIH) Campus
Building 31 in Bethesda, MD
June 23^rd - 24^th 2003

AGENDA, SLIDES and TRANSCRIPTS

Monday, June 23rd - Day 1
Time	Topic/Links to Slides	Presenter/Links to Transcripts
7:30 am–8:25 am	Continental breakfast
8:25 am–8:30 am	Welcome	Tom Insel & Ellen Stover, Ph.D.
8:30 am–9:00 am	Measurement and Treatment Research to Improve Cognition in Schizophrenia MATRICS-Rationale & Overview for	Wayne Fenton, M.D. Stephen Marder, M.D.
9:00 am–9:15 am	Goals of Meeting	Carol Tamminga, M.D. & Mark Geyer, Ph.D.
9:15 am–9:45 am	Domains of Cognition: Report from the Neurocognitive Committee Criteria for Cognitive Consensus Battery	Keith Nuechterlein, Ph.D. Michael Green, Ph. D.
9:45 am–10:00 am	Report from the Government-Industry Collaboration Committee	Dan Bush, M.D.
10:00 am–10:30 am	Report on the Neuropharmacology Interview Data	Bob Buchanan
10:30 am–10:40 am	Questions
10:40 am–11:00 am	Coffee Break
*Session 1: Jim Hagan, Chair
11:00 am–11:30 am	Dopaminergic targets	Patricia Goldman-Rakic
11:30 am–12:00 noon	Serotonergic targets	Bryan Roth
12:00 am–12:30 pm	Discussion	Jim Hagan
12:30 pm–1:30 pm	Working Lunch
*Session 2: Chris Schmidt, Chair
1:30 pm–2:00 pm	Adrenergic targets	Amy Arnsten
2:00 pm–2:30 pm	Glutamatergic targets: Ionotropic & Co-agonist	Joe Coyle
2:30 pm–3:00 pm	Glutamatergic targets: Metabotropic	Bita Moghaddam
3:00 pm–3:30 pm	Discussion	Chris Schmidt
3:30 pm–3:45 pm	Coffee break
*Session 3: Paul Cannon, Chair
3:45 pm–4:15 pm	Intracellular targets	Husseini Manji
4:15 pm–4:45 pm	Muscarinic targets	Joe Friedman
4:45 pm–5:15 pm	Discussion	Paul Cannon
6:00 pm–9:00 pm	Speakers and Chairs Dinner Meeting
Tuesday, June 24th - Day 2
7:00 am-8:00 am	Continental breakfast
*Session 4: Josee Leysen, Chair
8:00 am–8:30 am	Nicotinic Targets	Robert Freedman
8:30 am - 9:00 am	Anatomical Systems: Frontal Cortex	David Lewis
9:00 am - 9:30 am	Anatomical Systems: Limbic System	Paul Harrison
9:30 am - 10:00 am	Discussion	Josee Leysen
10:00 am–10:20 am	Coffee Break
*Session 5: Marc Brann, Chair
10:20 am–10:40 am	Regional cerebral blood flow/Activation tasks	Henry Holcomb
10:40 am–11:00 am	Imaging molecular targets	Richard Frank
11:00 am–11:15 am	Working memory: humans	Deanna Barch
11:15 am–11:30 am	Working memory: animals	Stacy Castner
11:30 am–12:00 noon	Discussion	Marc Brann
12:00 pm–1:00 pm	Working Lunch
*Session 6: : Jeff McKelvey, Chair
1:00 pm–1:15 pm	Pre-attentional processes: humans	David Braff
1:15 pm–1:30 pm	Pre-attentional processes: animals	Bart Ellenbroek
1:30 pm–1:45 pm	Attentional processes: humans TBN
1:45 pm–2:00 pm	Attentional processes: animals	Yogita Chudasama
2:00 pm–2:30 pm	Discussion	Jeff McKelvey
2:30 pm–2:45 pm	Coffee break
*Session 7: Richard Mailman, Chair
2:45 pm–3:00 pm	Learning & reference memory: humans	Brenda Kirchhoff
3:00 pm–3:15 pm	Learning & reference memory: animals	David Sweatt
3:15 pm–3:45 pm	Discussion	Richard Mailman
3:45 pm–4:15 pm	Fill-out questionnaire
4:15 pm–5:00 pm	Summation and next steps (Chairs)
5:00 pm	Adjourn

* Each presentation will be 20 minuntes followed by 10 minutes for discussion.

Revised: Sunday, 21-Sep-2003 21:44:22 PDT